Fig. 1

Production and purification of BMPs. A Schematics of BMPs production and purification. B Cell growth curve and Cmag curve of 42-L fermenter cultured MSR-1. Cell density is estimated by OD₅₆₅. Maximal Cmag value was1.6. Maximal OD₅₆₅ was 10.5. Total dry weight of collected BMP was 6.65 g. C Transmission electron microscopy image of the cultured MSR-1. BMPs were arranged in chains in the cell (arrow). D Purification of BMPs. Cells were disrupted by ultrasonication, and BMPs (black part) were separated by a magnet. E Transmission electron microscopy image of the purified BMPs