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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Iron oxide and iron oxyhydroxide nanoparticles impair SARS-CoV-2 infection of cultured cells

Fig. 3

FAC, Venofer and IONP uptake and localization in Vero E6 cells. A and B Evaluation of FAC, Venofer, FeraSpinR, APS-IONP-10, DMSA-IONP-10 and DMSA-IONP-16 internalization by Vero E6 cells after a 3, 6 and 24 h incubation at lower (20 or 50 μgFe/ml) (A) and higher (100 or 250 μgFe/ml) concentrations (B), as measured by ICP-OES. The graph shows the increase in iron content in Vero E6 cells over basal levels (untreated cells). The data (mean ± SD) are representative of three independent experiments. C Representative TEM images of Vero E6 cells after treatment with IONPs. High detail images showing the presence of IONPs in vesicles within the Vero E6 cells: scale bar 1 μm–100 nm. The vesicles containing the nanoparticles are indicated with arrows in the lower magnification images. Scale bar: 100 nm

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