Fig. 6
From: Iron oxide and iron oxyhydroxide nanoparticles impair SARS-CoV-2 infection of cultured cells
Ultrastructural analysis of infected cells treated with DMSA-IONP-10. A Normal condition: untreated and mock-infected Vero E6 cells (Control). B Infected condition: Vero E6 cells were infected at a MOI of 0.001 with SARS-CoV-2 for 24 h. C and D The cells were infected with SARS-CoV-2 and 1 hpi the cells were treated with DMSA-IONPs-10 at 250 μg Fe/ml (C) or alternatively, the cells were treated with DMSA-IONP-10 at 250 μg Fe/ml and then infected (D). In all cases the cells were processed for TEM of ultrathin sections at 24 hpi. Colored arrows indicate the presence of viral particles (in orange), DMVs (in green) and the accumulation of DMSA-IONP-10 inside the Vero E6 cells (in blue). Scale bars: 2 μm, 0.5 μm, and 100 nm, as indicated