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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Malting barley carbon dots-mediated oxidative stress promotes insulin resistance in mice via NF-κB pathway and MAPK cascade

Fig. 3

The oral administration of MBCDs disrupted glucose homeostasis in mice. a The blood glucose levels of mice tail veins. b Body weight. c Time course of changes and area under the curve (AUC) of blood glucose levels during the OGTT. d Time course of changes and AUC in blood insulin levels during the OGTT. e Time course of changes and AUC in blood glucose levels during the ITT. *p < 0.05 for L vs. C group, **p < 0.01 for L vs. C group, ***p < 0.001 for L vs. C group, #p < 0.05 for H vs. C group, ##p < 0.01 for H vs.C group, ###p < 0.001 for H vs. C group. Results are the mean ± SE (n = 8). f TUNEL assay apoptosis detection (FTIC) in liver cells. TUNEL (green) and nuclear (blue) constraining. TUNEL and nuclear staining are presented overlaid. DNase I was used as a TUNEL-positive control

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