Fig. 5From: Malting barley carbon dots-mediated oxidative stress promotes insulin resistance in mice via NF-κB pathway and MAPK cascadeMBCDs-induced oxidative stress activated NF-κB and MAPK pathway, leading to IR and gluconeogenesis. a, b Western analyses of NF-κB pathway in liver of mice at 16 weeks after oral administration of MBCDs with different concentrations. c, d Western analyses of MAPK pathway. e–g Western analyses of glucose metabolism-related proteins. h Gluconeogenesis-related genes were validated by RT–qPCR. *p < 0.05 for L vs. C group, #p < 0.05 for H vs. C group, ##p < 0.01 for H vs. C group. Results are the mean ± SE (n = 8)Back to article page