Fig. 4

3DSNA nanovaccine activated the innate and specific immunity by the NF-κB signaling pathway. A Schematic of 3DSNA as versatile adjuvants that initiate antigen-specific CTL responses for cancer immunotherapy. B The analysis of p-p65 by laser scanning confocal microscopy. C The survival of tumor-bearing mice treated with different formulations after tumor challenge. Reproduced with permission [71].