Fig. 5

A Viability assay performed in Caco-2 and Jurkat cancer cell lines using Pt precursor, IONP-Pt and IONP-Pt-Flu at different concentrations (1 and 0.1 mg/mL) incubating for 24–72 h. Results are reported as the mean number of live cells relative to the control (vehicle) from three independent experiments (significantly differences p * < 0.05, ** < 0.01). B Flow cytometry results (apoptosis and cell cycle assays) of NPs tested (IONP-Pt and IONP-Pt-Flu) for 24 h in Caco-2 cell line and Jurkat cancer cell lines at 0.1 mg/mL. Percentage of apoptotic cells (annexin+) and G2/M cells of each experiment are shown in the corresponding diagram as the mean of two independent experiments for each condition