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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Tumor-on-a-chip model for advancement of anti-cancer nano drug delivery system

Fig. 5

Evaluation of the therapeutic efficacy in TOCs. A Microfluidic TOC to assess the multifunctional liposome anticancer efficiency, (i) schematic illustration of the TOC device design and the TOC device after soft lithography, (ii) tumor suppressive effecta using tumor spheroid model, (iii) tumor suppression efficacy study using the TOC model. Reproduced with permission [58], Copyright 2019, John Wiley and Sons. B 3D microfluidic breast cancer-on-a-chip for determining the efficiency of PDT, (i) schematic illustration of the TOC device design, (ii) cell destruction was measured on both 2D monolayer culture and 3D microfluidic tissue culture 24 h after various PDT treatments. Reproduced with permission [59], Copyright 2015, RSC publications

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