Fig. 11From: Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinicalCopyright 2020, Wiley–VCHA The structure of TSSI and the process of TSSI NPs in the treatment of tumor with PDT-PTT synergistic therapy under the guidance of NIR-II FLI-PAI-PTI trimodal imaging. B Intracellular ROS level and live/dead cell staining of 4T1 cells after treatment under different conditions. C Thermal images, heating temperatures (at tumor sites) of 4T1-tumor-bearing BALB/c nude mice during continuous NIR irradiation at 12 h postinjection of TSSI NPs. Reproduced with permission [192].Back to article page