A The structure of BITT and schematic illustrations and the treatment of bladder cancer by NIR FLI-guided photo-enhanced chemotherapy. B Infrared thermography of bladder tumor mice 6 h after intravenous injection with PBS, BITT@BSA NPs, and BITT@BSA–DSP NPs, followed by laser irradiation (660 nm, 0.3 W cm–2, 10 min). C Average temperature of tumor regions. D Relative tumor volume growth curves of MB 49 tumor-bearing mice. E Representative tumor images of mice 12 days after different treatments. Reproduced with permission .