Fig. 4From: Lactobacillus cell envelope-coated nanoparticles for antibiotic delivery against cariogenic biofilm and dental cariesIntegration of PLAG-NPs and LA/PLGA-NPs into the S. mutans biofilm structure. A–E CLSM images of the penetration depth of PLAG-NPs (blue) and LA/PLGA-NPs (red/blue) in the biofilms. F 3D CLSM images of the spatial distribution of LA/PLGA-NPs (red/blue) and PLGA-NPs (blue) in S. mutans (green) biofilms. Scale bar = 100 μm. G Quantitative data of the fluorescence volume of PLGA-NPs and LA/PLGA-NPs in S. mutans biofilms. H Inhibitory effect of LA/PLGA-NPs on S. mutans biofilms. All assays were performed three times, and the data are expressed as the mean ± standard error of the meanBack to article page