Fig. 3
From: Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy
TPP-SS-ATS-LS on proliferation of breast cells and targeting ability. A The cytotoxicity of TPP-SS-ATS-LS Dose response curves of the cytotoxic effects of TPP-SS-ATS-LS in 3 breast tumor cell lines. Data represent the means of triplicate samples ± standard error (SD, n = 3). B Effect of TPP-SS-ATS-LS on the ability of cells monoclonal forming. C Confocal images of MDA-MB-231 cells incubated with TPP-SS-ATS-LS for continuous period. TPP-SS-ATS-LS entry into mitochondria begins at 6 h (green fluorescent spot), and gradually accumulates in the mitochondria during the detected 48 h. (scale bar: 50 μm)