Fig. 7
From: Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing
GSH-responsive CRISPR-Cas9 delivery nanoformulations. A Illustration of the multifunctional SNP for the delivery of nucleic acids (e.g., DNA and mRNA) and CRISPR genome editor (e.g., RNP, RNP + ssODN), and the intracellular trafficking pathways of SNP. Reproduced with permission [128]. B Illustration of formulating bioreducible lipid/Cas9 mRNA/sgRNA nanoparticle for CRISPR-Cas9 genome editing delivery in vitro and in vivo. Reproduced with permission [129]