Fig. 1

Characterization of hucMSC-sEVs. a The size and morphology were measured by TEM (scale: 200 nm). b, c The appearance and height of the hucMSC-sEVs were determined by AFM. d The expression of positive and negative characteristic markers of the hucMSC-sEVs were detected by western blotting. e, f Particle size, concentration, and zeta potential of hucMSC-sEVs determined by NTA. g, h MiRNA sequencing was performed to evaluate small RNA molecules enriched in the hucMSC-sEVs