Fig. 4From: Nanocarriers for effective delivery: modulation of innate immunity for the management of infections and the associated complicationsReproduced with permission from reference [230]Schematic diagrams showing a ERN1 as an inhibitor of MyD88-dependent TLR pathway that regulates the expression of cell pro-inflammatory cytokine; b IRE1α as a regulator to control the intracellular concentration of Ca2+ ion and macrophage polarization.Back to article page