Table 2 Comparison of the methods to detect PSD95

Method

Western blotting

NMR spectroscopy

Fluorescence imaging

Fluorescence detection

Main advantages

High sensitivity, high selectivity

Detection of conformational changes

Enhancement of detection signal

Low cost, high sensitivity, high-throughput screening

Limitation

Only qualitative analysis

Difficulty in high-throughput screening

Limited recycle number

Reference

[42]

[43]

[44]

This work