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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Mechanisms of chemotherapeutic resistance and the application of targeted nanoparticles for enhanced chemotherapy in colorectal cancer

Fig. 3

(Reproduced with permission from [133]. © 2020 by Ana Luiza C. de S. L. Oliveira et al.)

Effects of oxaliplatin and retinoic acid loaded in cholesterol-coated PLGA NPs on tumor cells. a AFM images of Control group, NPs 1 group and NPs 2 group; fluorescence images display the internalization of NPs by CT26 cells, with monitored NPs in yellow; b Cell viability of SW-480 cells after treatment with different concentrations of OXA and PLGA NPs for 24 h; c Changes in tumor volume after treatment with different concentrations of OXA and PLGA NPs in a subcutaneous transplantation tumor model in mice; d Tumor growth curves for each group were compared with the negative control group

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