Fig. 5From: Mechanisms of chemotherapeutic resistance and the application of targeted nanoparticles for enhanced chemotherapy in colorectal cancer(Reproduced with permission from [150]. © 2020 Elsevier Ltd)Redox-responsive NPs prepared on the basis of xylan-lipoic acid for the delivery of niclosamide for the treatment of CRC. a Schematic diagram of the preparation of Xyl-LA/Nic NPs; b stability and degradation of Xyl-LA/Nic NPs at different pH; c drug release rate of Xyl-LA/Nic NPs at different pH and in the presence or absence of GSH Back to article page