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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Mechanisms of chemotherapeutic resistance and the application of targeted nanoparticles for enhanced chemotherapy in colorectal cancer

Fig. 7

(Reproduced with permission from [168]. © 2019 American Chemical Society)

EpCAM aptamer-functionalized cationic liposome NPs loaded with miR-139-5p inhibited CRC cells. a Schematic diagram of the preparation method of NPs and ANPs; b fluorescence images of HCT116 subcutaneously transplanted tumor-bearing mice after tail vein injection of free DiR, DiR-NPs and DiR-ANPs, revealing the in vivo targeting and distribution of ANPs; c tumor volume changes after group treatment in HCT8 tumor-bearing mice

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