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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Two-dimensional Ti3C2Tx MXene promotes electrophysiological maturation of neural circuits

Fig. 8

Ti3C2Tx MXene increased the frequency but not the amplitude of spontaneous synaptic currents in NSC-derived neurons. A and B Representative dual staining images of PSD95 and Synapsin-1 at 7 DIV for typical neuron cultured on TCPS and MXenes, Scale bar = 10 μm. (A) and the average number of synapses (B). C Typical spontaneous excitatory postsynaptic currents (EPSCs) recorded from two new neurons. D and E Average of EPSC amplitudes across different cells (D) and cumulative amplitude distribution of two new neurons (E). F and G Average of EPSC frequencies across different cells (F) and cumulative interevent interval distribution of two new neurons (G). * indicates p < 0.05

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