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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy

Fig. 3

Efficient escape of Stealth exosome from the MPS. A Schematic illustration of these experiments. B Representative images show exosomes uptake by RAW264.7 cells. Different groups of exosomes were labelled with DiO and then incubated for 4 h/12 h/24 h. Cells were stained with Hoechst. Images were taken under fluorescence microscope. Scale bar = 20 μm. C Representative in vitro fluorescent images of the DiR-labeled exosomes in tumors and main organs. n = 6 mice. D qPCR analysis of relative expression of Cel-miR-54 in various organs and tumors of mice treated with Natural Exo and Stealth Exo. U6 served as an internal control. Data are expressed as mean ± SEM of six independent biological samples. *p < 0.05 by t-test

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