Fig. 2

Characterization of HAOPTs. A Size distribution, z-average diameter and surface zeta potential of OPTs, DexOPTs and HAOPTs. Data were represented as mean ± SD (n = 3). B TEM images of OPTs and HAOPTs. Scale bar, 100 nm. C Z-average diameter alterations of different micelles (OPTs, DexOPTs and HAOPTs) with incubation in PBS at 4 °C for 12 days. Data were represented as mean ± SD (n = 3). D Plots of the fluorescence intensity ratio of 384 nm and 373 nm to the logarithm concentration of HAOPTs