Fig. 2

Excellent anti-tumor ability of RuPOP@MCM in vitro. A Scheme of RuPOP@MCM treatment to kill MDA-MB-231 tumor cells. B IC₅₀ of MDA-MB-231cells treated with different concentrations of RuPOP and RuPOP@MCM for 72 h. C-D Anti-invasion effect assay of RuPOP or MCM@RuPOP on MDA-MB-231 cells. E Wound healing assay of RuPOP or RuPOP@MCM on MDA-MB-231 cells (scale bar = 100 μm). F Cellular uptake of RuPOP@MCM on MDA-MB-231 cells at different time. G Intracellular localization of RuPOP@MCM in MDA-MB-231 cells. The cytoskeleton was labeled with Alexa Fluor 488 phalloidin (green fluorescence), and nucleus was labeled with Hoechst 33,342 (blue fluorescence). H Morphology of RuPOP@MCM and RuPOP@KCM after incubation with lysozyme for 12 h, 48 h, 72 h