Fig. 4

The anticancer mechanism of RuPOP@CM in vitro. A Schematic illustration of RuPOP@CM triggering excess ROS generation and accelerating cell apoptosis and cell cycle arrest. B The formation of MDA-MB-231 tumor spheroids. C Inhibition curves of different concentrations of RuPOP and RuPOP@MCM on tumor spheroids. D Flow cytometric analysis on the cell cycle of MDA-MB-231 cells and K562 cells after treatment with different concentrations of RuPOP@MCM and RuPOP for 72 h