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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Directing ricin-based immunotoxins with targeting affibodies and KDEL signal peptide to cancer cells effectively induces apoptosis and tumor suppression

Fig. 4

Fluorescence images of SK-BR-3 cells treated with HER2Afb-RTA (A, C) or HER2Afb-RTA-KDEL (B, D) at various time points. A, B Nuclei, RTA, and TfR are shown in blue, green, and red, respectively. C, D Nuclei, RTA, and VPS26A are shown in blue, green, and red, respectively. Co-localization of RTA and TfR (A, B at 2 h) or RTA and VPS26A (C, D at 4 h) was also analyzed with a line intensity profile according to distance. The analyzed lines are indicated as white arrows. Scale bars, 10 μm

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