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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: An ischemia-homing bioengineered nano-scavenger for specifically alleviating multiple pathogeneses in ischemic stroke

Fig. 5

The in vivo therapeutic effects of the TPC@M2 NPs against ischemic stroke. a Diagram process of MCAO animal experiment. b Representative images of TTC-stained brain slice and c the corresponding quantification of infarct volume in different groups (n = 10). d Representative images of ROS levels in the brain after different treatments. Scale bar: 100 μm. e Representative images and MFI of the CD16/32 and the CD206 (red: CD206; green: CD16/32; blue: DAPI; scale bar: 100 µm) in brain treated with different groups. f Representative immunohistochemical analysis of the brain tissues in MCAO rats of different groups using H&E (up) and TUNEL (down) staining. g The neurological score of the MCAO-rat in different groups (n = 10). Results are presented as means ± s.d. *P < 0.05, **P < 0.01, and ***P < 0.001 determined by Student’s t-test

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