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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

Fig. 5

Reproduced with permission from Ref. [168] Copyright 2019, American Chemical Society. B Immunohistochemical imaging of female and male human amniotic stem cells (hAMSCs) demonstrated a significant increase in QD uptake in female vs male cells. The scale bar represents 50 μm in all panels. (C) QD uptake was quantified using confocal images (n = 7/group). Reproduced with permission from Ref. [169] Copyright 2018, American Chemical Society

Effect of cell age and sex on uptake of nanoparticles. A Fluorescence micrographs of NP colocalization in lysosomes of young IMR90 and senescent IMR90 cells. Experiments were conducted at 37 °C for 2 h. Lysosomes were stained with LysoTracker Blue fluorescent dye (blue) and quantum dots (QD)/QD-HC red marked nanoparticles. Bar = 50 μm.

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