Fig. 6
From: Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery
The general scheme of bioconjugation reactions for the synthesis of drug-loaded nanobiohybrid carriers. Step A: NPs are first functionalized with a chemical partner and then loaded with the therapeutic agent of choice. Step B: The chemical group is also incorporated into the surface of bacteria. Step C: Bioconjugation reaction between the chemical partners leads to the bioconjugate bacteria-nanomaterial