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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Identification and ultrasensitive photoelectrochemical detection of LncNR_040117: a biomarker of recurrent miscarriage and antiphospholipid antibody syndrome in platelet-derived microparticles

Fig. 8

a Photocurrents and b EIS of the proposed PEC biosensor: (i) g-C3N4/GCE, (ii) β-In2S3/GCE, (iii) β-In2S3@g-C3N4/GCE, (iv) Au NPs/β-In2S3@g-C3N4/GCE, (v) probe/Au NPs/β-In2S3@g-C3N4/GCE, (vi) MCH/probe/Au NPs/β-In2S3@g-C3N4/GCE (the voltage was 0.08 V; the AC sine wave amplitude was 10 mV; the scan frequency range was 8 × 105–10 Hz). c Photocurrent responses under different LncNR_040117 concentrations: 0, 0.1, 1, 10, 102, 103, 104, 105, 106 fM. d Calibration line of photocurrent against the concentration of LncNR_040117 (n = 3, mean ± s.d.). e Photocurrent responses and f calculated concentrations of different sequences. Where i–v represent LncNR_040117, SNHG15 LncNR_152596.1, HOXA-AS2 LncNR_122069.1, RMRP LncNR_003051.3, and LUCAT1 LncNR_103548.1, respectively (n = 3, mean ± s.d.). g Photocurrent signal under 15 continuous radiation cycles at a LncNR_040117 concentration of 1 fM. h Detection results of LncNR_040117 concentrations in clinical serum samples by PEC biosensor and RT-qPCR method (n = 3, mean ± s.d.)

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