Fig. 2

Exosomal molecules and corresponding pathways in the exosome-mediated interactions between sarcoma cells and TME cells. The dotted arrow indicates the transfer of exosomes from TME cells to sarcoma cells, while the solid arrow represents the transfer from sarcoma cells to TME cells. The oval with frame line contains the effective molecules in exosome transport. The color of each oval corresponds to the origin of the exosomes, where orange denotes sarcoma cell-derived exosomes, blue denotes TAM-derived exosomes, red denotes MSC-derived exosomes, and purple denotes CAF-derived exosomes. The box covers the corresponding pathways activated by exosomes