Fig. 4From: Repositioning of drugs for Parkinson’s disease and pharmaceutical nanotechnology tools for their optimizationa Increased specificity towards BBB. The surface coating of NPs with suitable materials can increase the specificity towards the BBB; these materials (as mentioned in Table 2) can be polymers, proteins, antibodies, peptides, and other additives. b Receptor-mediated transcytosis. The passage through the BBB is exemplified through receptor-mediated transcytosis. A very frequently used pathway for the transport of NPs to the brain, for this use, is assembled with specific receptors found in the BBBBack to article page