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Table 1 Diagnostic Nanocarriers Delivery Agents for Hepatocellular Carcinoma

From: Emerging nanobiotechnology for precise theranostics of hepatocellular carcinoma

Nanocarriers

Diagnostic Agent

Technique

Target cell

References

Nanobubbles (NBs)

Nanobubbles;

Pro-bexarotene NBs;

NBs-GPC3-rGO;

Poly(oxalate-co-curcumin) (POC)

Ultrasound imaging;

Nano-knife

HCC cell lines, HepG2

[54, 55]

Dendrimer

Polydopamine

CT and PTT

HepG2

[56, 57]

Carbon Dots (CDs)

Gd

MRI

HepG2

[58]

Calcium phosphate NPs

Gd-DTPA

MRI

BEL-7402,HepG2

[59]

Silica NPs

Gd;

Gold NPs

MRI and PDT

BNL 1 ME A. 7R.1 cell

[60, 61]

Graphene Oxide-Based Nanocarriers

Gd

MRI

Human hepatoma cells

[62,63,64]

Metal oxide NPs (Iron, Zinc)

Gd

MRI

HepG2

[65, 66]

Superparamagnetic Iron-Oxide NPs(SPIONs)

Gd;

Iron oxide

MRI

HCC cell lines

[67,68,69]

Micelles

Micelles;

SPION;

Gd

MRI/UCL

HepG2

[70, 71]

Lipid NPs;

Vesicle NPs;

Liposome

Gd;

Quantum dots

MRI/PAI

HepG2

[72,73,74]

Polymeric NPs

Gd-DTPA;

SPION

MRI

HCC cell lines

[75, 76]