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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Targeting therapy and tumor microenvironment remodeling of triple-negative breast cancer by ginsenoside Rg3 based liposomes

Fig. 6

Enhanced tumor penetration ability of Rg3-Lp. (A) Fluorescence analysis of the 3D 4T1/3T3 tumoral spheroids accumulation and penetration of C-Lp/C6 and Rg3-Lp/C6 by confocal microscopy imaging. scale bar: 100 μm. (B) Penetration depth of different C6-loaded liposomes into 4T1/3T3 spheroid. (n = 3). Qualitative analysis of the signal of CAFs (C) identified by α-SMA antibody staining (blue) and (D) apoptotic tumor cells identified by TUNEL staining (green) in tumor section after different treatment. Scale bar: 2 mm. ***p < 0.001; Unpaired t-test was used for analysis of differences between two groups. Error bars represent mean ± SD of three independent experiments

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