Fig. 4
From: Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer
Different nanoparticles designed to overcome cancer MDR. Organic, lipid, polymer, metallic and quantum dots-based nanomaterials decorated with ligands for the co-delivery of chemotherapeutic drugs and siRNA to overcome cancer MDR in resistant cells. The drugs are released in the cancer cells in response to external stimuli, resulting in the inhibition of ABC drug efflux pumps, thereby sensitizing multidrug-resistant cells