Fig. 8
HE staining of the organs (a), Ki67 staining (b), proportion of proliferation (d), TUNEL staining (c) and proportion of apoptosis (e) of the tumor tissues obtained from the tumor-bearing female BALB/c mice treated with different preparations. All the pictures were gained under the magnification of 400×. Scale bar = 50 μm. A: N.S., B: Sal A solution, C: NLC-Sal A, D: DOX solution, E: DOX injection, F: Sal A/DOX solution, G: NLC-DOX, H: NLC-Sal A/DOX, I: E-[c(RGDfK)2]/FA-NLC-Sal A/DOX. **p < 0.01 vs DOX injection, ***p < 0.001 vs DOX injection, △△p < 0.01 vs DOX solution, △△△p < 0.001 vs DOX solution. Results are expressed as mean ± SD, n = 6