Fig. 5

HHP-EXO inhibits TAC-induced expression of hypertrophy markers and the activation of ERK, AKT, STAT3 signaling pathways. A Representative images of Western blot showing the expression of β-MHC, BNP, GP130, STAT3, p-STAT3, ERK, p-ERK1/2, AKT and p-AKT in left ventricular tissues among different treatments. B Quantification of the expression of β-MHC, BNP and GP130 among groups (n = 4–7). C Quantification of the ratios of p-STAT3/STAT3, p-ERK1/2/ERK, and p-AKT/AKT among groups (n = 4–7). Protein expression was normalized to that of GAPDH. Data are presented as Mean ± SEM, with *P < 0.05 and **P < 0.01