Fig. 3
From: Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy
Assessing the specificity of the HSTP1 to aHSCs by immunofluorescence histochemistry. A aHSCs and HSTP1 co-immunofluorescence in fibrotic and normal liver tissues. The aHSCs were stained with anti-α-SMA antibody (red), FITC-labeled HSTP1 (green), nuclei were visualized by counterstaining with DAPI (blue), and images were merged. B Co-immunofluorescence for HSTP1, rcHSTP1 (green) and α-SMA (red) in fibrotic liver tissues. C Co-immunofluorescence for HSTP1, rcHSTP1 (green) and α-SMA (red) in lung tissues. The bar graphs depict the Manders’ coefficients M1 and M2 in colocalization. Scale bar: 50 µm. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001