Fig. 6
From: Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy
Binding of HSTP1-Exos to HSC-T6 cells in vitro. A, B Flow cytometric analysis of Blank-Exos, Lamp2b-Exos, and HSTP1-Exos labeled with Dil binding to HSC-T6 cells. The percentages represent the proportion of HSC-T6 cell that had internalized Dil-labeled exosomes (Dil-positive HSC-T6 cells) at 1 h and 3 h. C, D Confocal microscopy images of colocalization of Dil-labeled Blank-Exos, Lamp2b-Exos, and HSTP1-Exos (red) and DiO labeled cell membrane (green) at 1 h and 3 h. Cell nuclei were stained with DAPI (blue). Scale bars: 10 µm. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001