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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury

Fig. 6

MiRNA regulation of Nrf2 in MIRI (2). A Interference efficiency of the inhibitor of 4 miRNAs. B Overexpression efficiency of mimics of the 4 miRNAs. C qPCR detection of Nrf2 expression after interference with the 4 miRNAs. D qPCR detection of Nrf2 expression after overexpression of the 4 miRNAs. E WB detection of Nrf2 expression after interference with the 4 miRNAs. F WB detection of Nrf2 expression after overexpression of the 4 miRNAs. G Dual luciferase reporter gene assay of the 4 miRNAs with Nrf2. H Assessment of ROS, total SOD activity, MDA, GPx enzyme activity and LDH cytotoxicity in H9C2 cells after interference with the 3 miRNAs. I Assessment of ROS, total SOD activity, MDA, GPx enzyme activity and LDH cytotoxicity in H9C2 cells after overexpression of the 3 miRNAs. ns no significance; *P < 0.05; **P < 0.01; *** P < 0.001; **** P < 0.0001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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