Fig. 4From: Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy toward uveal melanoma based on a dual-modal imaging-guided manganese metal–organic framework nanoparticlesSchematic of key steps involved in preparation of porous ICG-COP@MOF-PR (ICG-siOUM1 + siPTPRZ1 + Cis@MOF-PR) nanostructures and their associated major mechanistic pathways in cancer therapyBack to article page