Fig. 5
From: BMSC exosome-enriched acellular fish scale scaffolds promote bone regeneration
Enhanced osteogenic induction by OBMSC-Exos in vitro. (a, b) The size distribution of the microvesicle fraction isolated from osteogenic OBMSCs. Scale bar was 100Â nm. (c) Western blot results of the expression of specific markers of exosomes (CD63 and TSG101). (d) Relative ALP activity of BMSCs treated with or without OBMSC-Exos for 7 days. (e) Q-PCR analysis of Runx2, Col1a1 and OPN expression in BMSCs treated with or without OBMSC-Exos for 7 days. (f) Western blot analysis of RUNX2, Collagen I and OPN expression in BMSCs treated with or without OBMSC-Exos for 7 days