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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Serpin-loaded extracellular vesicles promote tissue repair in a mouse model of impaired wound healing

Fig. 3

Proteomic analysis of EV protein payloads isolated from WT vs. db/db donors. a A heatmap of protein expression in WT and db/db EVs showing protein levels elevated in WT EVs compared to db/db EVs, and protein levels in WT EVs that are lower than db/db EVs. n = 3 independent animals of each genotype. b Volcano plot showing that the standard deviation of EV proteins identified and magnitude of fold-changes that support the high statistical significance of EV proteins identified. n = 3 biological replicates for each genotype. c String analysis of predicted proteins that may interact with SERPINA1 (red symbol), d SERPINF2 (red symbol), and e SERPING1 (red symbol). All representative images showed as observed in three independent experiments

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