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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Erythropoietin-PLGA-PEG as a local treatment to promote functional recovery and neurovascular regeneration after peripheral nerve injury

Fig. 9

Effects of EPO-PLGA-PEG on whole-mount nerve angiogenesis post-crush injury. A Representative CD31-stained whole-mount images to show blood vessel formation. B Blood vessel density is shown as the percentage of number of blood vessels in total area. C Branching of blood vessels is shown as the number of blood vessel junctions/mm2 (n = 5/group; mean ± SEM; *p < 0.05, **p < 0.01, and ***p < 0.001 vs. saline group; σp < 0.05 and σσσp < 0.001 vs. PLGA-PEG group; #p < 0.05, ##p < 0.01, and ###p < 0.001 vs. uninjured group; scale bar = 100 μm). Each image represents 3 images from 5 different SNs, for a total of 15 images analyzed per group

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