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Table 2 Representation of the main physicochemical characteristics of SiO2 (nano)particles

From: Pitfalls in methods to study colocalization of nanoparticles in mouse macrophage lysosomes

(Nano)Particles

TEM5

DLS6

Milli-Q

cRPMI

dc [nm]1

dh [nm]2

t = 0 h

dh [nm]2

t = 24 h

PDI3

ζ [mV]4

dh [nm]2

t = 0 h

dh [nm]2

t = 24 h

SiO2-BDP FL

59 ± 6

77 ± 0

76 ± 1

0.2

− 52 ± 2

91 ± 2

87 ± 3

SiO2-RhoB

59 ± 5

71 ± 1

72 ± 1

0.04

− 34 ± 1

82 ± 4

69 ± 3

SiO2-Cy5

119 ± 10

134 ± 2

139 ± 3

0.04

− 44 ± 2

93 ± 10

108 ± 4

SiO2-Cy5

920 ± 88

820 ± 3

847 ± 6

0.03

− 44 ± 1

825 ± 11

941 ± 10

  1. 1core diameter; 2hydrodynamic diameter; 3polydispersity index; 4zeta potential; 5transmission electron microscopy; 6dynamic light scattering. Particles: SiO2-Bodipy® fluorescein NHS ester (BDP FL), SiO2-Rhodamine B (RhoB), SiO2-Cyanine 5 (Cy5)