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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Scalable and high-throughput production of an injectable platelet-rich plasma (PRP)/cell-laden microcarrier/hydrogel composite system for hair follicle tissue engineering

Fig. 7

PRP-loaded DECHS improves the HF inductive ability. (a) Schematic diagram of injecting PRP-loaded DECHS into a nude mouse; (b) in vivo fluorescence imaging following subcutaneous injection of DIO-labeled cells in the control group, DECHS group, and PRP-loaded DECHS group. (c) Quantitative diagram of the DIO signal intensity expressed as photons/s/cm2/sr. Stereomicroscopy images of injection sites in the control group (d–f), DECHS group (g–i), and PRP-loaded DECHS group (j–l). HE-stained images of the injection site in the control group (m, n), DECHS group (o, p), and PRP-loaded DECHS group (q, r). Black arrows: regenerative HFs, yellow: regenerative blood vessels. Statistical diagrams of HF numbers/sample (s); and blood vessel numbers/sample (t) among the three groups. *p < 0.05; **p < 0.01; ***p < 0.001; statistical significance was analyzed using unpaired independent-samples t-test

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