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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Antibiofilm activity of ultra-small gold nanoclusters against Fusobacterium nucleatum in dental plaque biofilms

Fig. 6

Effects of topical AuNCs treatment on periodontal inflammation and bone loss. A H&E staining of tissue sections from the maxillary of mice. Red arrows indicate inflammatory cell infiltration. Black arrows indicate epithelial destruction. M2 indicates the second molar, and M3 indicates the third molar. B RT-qPCR analysis of relative mRNA levels, and C IHC staining of the protein levels of the inflammatory cytokines IL-1β, IL-6, TNF-α, and IL-10. D 3D micro-CT reconstructed images of maxillary molar area. E Alveolar bone parameters assessed by micro-CT. Con treatment with PBS, Lig ligature and treatment with PBS, Fn ligature with F. nucleatum inoculation, AuNCs ligature with alternate applications of F. nucleatum and AuNCs (0.4 mM). *P < 0.05, **P < 0.01, ***P < 0.001

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