Fig. 9
From: Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
Immunohistochemical analysis of the femur samples from the different experimental groups: Control (0.9% saline solution), Apt-LPNPs-Cntrl and Apt-LPNPs-SFRP1. A Semipanoramic images of cortical bone showing the presence of Col I and OCN immunoreactivity. Scale bar: 50 µm. B Graphs showing the relative staining intensity of Col I and OCN in the three experimental groups. Histograms represent mean ± SEM values. (*) denotes statistical significance between Control and Apt-LPNPs-Cntrl to Apt-LPNPs-SFRP1 (p < 0.05) (n = 6)