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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia

Fig. 1

Formulation and characterization of Sora-MNC. A Schematic diagram illustrating the self-assembly of Sora-MNC and centrifugal filtration process for purification. B Z-average size, C drug loading efficiency and D drug loading content of Sora-MNC prepared from HA-EGCG and sorafenib at varying final concentrations. Results are reported as mean values (n = 3). E Particle size distribution and F TEM images of Sora-MNC-1. G Stability of Sora-MNC-1 in 10% (v/v) fetal bovine serum over 5 days. H Cumulative sorafenib release and I derived count rate of Sora-MNC-1 over 4 d incubation in 10 mM PBS (pH 7.4) without or with either 100 mM urea or 0.1% Tween-20. Mean ± SD (n = 3). J Particle size distribution of Sora-MNC-1 measured after 6 h incubation in 10 mM PBS (pH 7.4) without or with either 100 mM urea or 0.1% Tween-20

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