Fig. 3

Flow cytometric analysis. A Scheme for CD44-mediated targeting of Sora-MNC and induction of terminal differentiation and apoptosis. B Cellular binding of DyLight488-labeled MNC on MOLM-14 and MV-4-11 cells after 1 h incubation without or with excess dextran or HA. C Representative scatter plots and D quantification of CD14⁺CD11b⁺ population in MOLM-14 and MV-4-11 cells treated with free sorafenib, HA-EGCG, Sora-MNC or ATRA. E Representative scatter plots of FITC-Annexin V/PI staining and F quantification of apoptotic population in MOLM-14 and MV-4-11 cells treated with free sorafenib, HA-EGCG, Sora-MNC or ATRA.