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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Thrombus-specific/responsive biomimetic nanomedicine for spatiotemporal thrombolysis and alleviation of myocardial ischemia/reperfusion injury

Fig. 1

Schematic illustration of PTPN preparation and rescue of ischemia and reperfusion injury. a Synthesis method of PTPN. b During the ischemia period, PTPN targets the thrombus via platelet membrane and is degraded in response to the acidic microenvironment, thereby releasing tPA to re-open the infarcted artery. During the reperfusion period, antioxidant protocatechualdehyde (PC) is released to clear ROS for cardiomyocyte mitochondria protection

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Journal of Nanobiotechnology

ISSN: 1477-3155

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